- Calcium Salts + Glucaric Acid = Calcium D-Glucarate.
- An important compound with a growing field of study and research.
- Formula with vitamin B6 in the form of highly bioavailable Pyridoxine HCl.
- Ideal compound for middle-aged women and bodybuilding and fitness athletes.
- Naturally occurring compound in the body. It is synthesized via glucuronic acid.
- High concentration: 500mg of pure Calcium D-Glucarate per vegetable capsule.
- Suitable for vegetarian and vegan diets.
Calcium D-Glucarate 500mg - Source of D-Glucaric Acid
Calcium D-Glucarate 500mg from EssentialSeries, is a dietary supplement from HSN developed from the calcium salt of D-glucaric acid, the most representative and scientifically researched form of the compound. The formula has been developed with a highly bioavailable form of Vitamin B6 to support the action of the compound.
Calcium D-glucarate is the calcium salt of D-glucaric acid, a naturally occurring substance in small amounts in mammals, including humans. Glucaric acid is also found in many fruits and vegetables, with the highest concentrations found in oranges, apples, grapefruits, and cruciferous vegetables.
HSN's Calcium D-Glucarate is a widely used dietary supplement by adult women and bodybuilders for its nutritional characteristics, in addition to being a vegan compound compatible with all types of diets as it does not provide calories or contain allergens.
Calcium Glucarate and Vitamin B6 Formula
Calcium Glucarate as the main source of D-Glucaric Acid
D-Glucaric acid is the compound that has the nutritional relevance of the Calcium Glucarate form.
D-Glucaric acid is not provided in free form since its stability and bioavailability require association with ions such as calcium, in this case, or with potassium, for example.
Calcium D-glucarate hydrolyzes into free calcium and D-glucaric acid after introduction into an acidic environment (stomach acid) and then D-glucaric acid is metabolized into one of two metabolites; D-glucaro-1,4-lactone (30% of ingested D-glucaric acid) or D-glucaro-6,3-lactone (also 30%) while 40% remains as D-glucaric acid.
Therefore, the nutritional interest in Calcium D-Glucarate lies in the stability of the form itself, and in the nutritional properties of D-Glucaric Acid it contains, in addition to the metabolites generated from it.
Naturally occurring compound in the body. Quality control and high purity
D-Glucaric acid is not something foreign to us, humans internally generate D-glucaric acid through a metabolic pathway via D-glucuronic acid. In addition, D-glucarate or D-glucaric acid is also very present in fruits and vegetables commonly consumed.
At HSN, we develop high-quality nutritional D-glucarate calcium and excellent quality controls to ensure what we consider indispensable:
Quality + Effectiveness + Safety of compounds
Perfect for you and your daily nutrition.
Composition without the use of additives for aesthetic reasons
Calcium D-Glucarate can be developed in many ways, not only as a compound itself but as a product.
We are clear about this and want to offer you more with less:
We develop pure calcium glucarate simply and without additives from the compound purification process, while the product is developed in vegetable capsules, without dyes or other aesthetic additives, our products have the natural appearance they should have, so you enjoy more:
A pure quality formula of D-glucaric acid in calcium salt, with vitamin B6, without all the things you don't need.
High concentration per vegetable capsule - Doses supported by research
At HSN, we review the scientific research supporting the use of each of the compounds we work with.
And we have developed a highly concentrated Calcium D-Glucarate with half a gram of compound in each vegetable capsule, with a recommended daily dose of 3 capsules our product provides 1500mg of pure Calcium D-Glucarate daily.
Composition with vitamin B6 for hormonal support
We have developed our Calcium D-Glucarate formula with a significant contribution of Vitamin B6, also known as pyridoxine, in a form (hydrochloride, HCl) of high absorption and general bioavailability.
Vitamin B6 plays important roles in the body, although we add it to Calcium D-Glucarate for a key role as it helps regulate hormonal activity.
Natural sources of Calcium Glucarate compared to a supplement
Although there are natural sources of D-glucaric acid, especially found in fruits and vegetables, their concentration is very low. Oranges, carrots, spinach, apples, broccoli, alfalfa sprouts, and potatoes stand out.
However, even though oranges are by far the source with the highest glucaric acid content in the diet, they only provide 4-5mg per 100g of fruit.
Our Calcium D-Glucarate provides 1500mg of pure Calcium D-Glucarate per daily dose, making it the ideal support for people looking to make use of this important and increasingly studied nutrient.
Combine it with other products for synergistic activity! We help you choose
Calcium glucarate can be combined with multiple compounds, as it has no contraindications to combined use with any common dietary supplement nutrient, to the best of our knowledge.
However, when we talk about synergistic combination, we refer to combined use with other compounds that have nutritional sense for combined use, and in this case, there is one that combines with Calcium Glucarate above others: Resveratrol.
Combine resveratrol with Calcium D-glucarate for an unbeatable combo.
References:
- Zółtaszek, R., Hanausek, M., Kiliańska, Z. M., & Walaszek, Z. (2008). Biologiczna rola kwasu D-glukarowego i jego pochodnych; potencjalne zastosowanie w medycynie. Postepy Higieny i Medycyny Doswiadczalnej, 62, 451–462.
- Walaszek, Z., Szemraj, J., Narog, M., Adams, A. K., Kilgore, J., Sherman, U., & Hanausek, M. (1997). Metabolism, uptake, and excretion of a D-glucaric acid salt and its potential use in cancer prevention. Cancer Detection and Prevention, 21(2), 178–190.
- Dwivedi, C., Heck, W. J., Downie, A. A., Larroya, S., & Webb, T. E. (1990). Effect of calcium glucarate on β-glucuronidase activity and glucarate content of certain vegetables and fruits. Biochemical Medicine and Metabolic Biology, 43(2), 83–92.
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