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PQQ Disodium Salt 20mg. Stable form of Pyrroloquinoline Quinone. PQQ Reduced tested by absorbance. Purity tested by HPLC (>99.0%). Obtained by bacterial biosynthesis through vegetal fermentation processes. Free of Genetically Modified Organisms. Formula with B vitamins and vitamin E. Safe + effective composition. Suitable for vegans.
Fish Free
Lactose Free
Dairy Free
Nut Free
Suitable for Vegans
Suitable for Vegetarians
Without GMOs
Egg Free
Gluten Free
Soy Free
Minimum purchase of units!
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NightServings: 120
| Field | Per serving | Daily amount | NRV* | NRV* |
|---|---|---|---|---|
Disodium salt of pyrroloquinoline quinone | 20 mg | 20 mg | ++ | ++ |
Pyrroloquinoline quinone | 15.4 mg | 15.4 mg | ++ | ++ |
Pantothenic Acid | 6 mg | 6 mg | 101% | 101% |
of calcium D-pantothenate | 6.6 mg | 6.6 mg | ++ | ++ |
Vitamin E | 3.6 mg | 3.6 mg | 30% | 30% |
of D-alpha-tocopheryl acid succinate | 4.4 mg | 4.4 mg | ++ | ++ |
Vitamin B2 (as riboflavin) | 1.4 mg | 1.4 mg | 100% | 100% |
NRVs (Nutrient Reference Values) established in Regulation (EU) 1169/2011 of 25 October 2011. †† NRVs are not established on this occasion.
Ingredients
Corn starch, vegetable capsule [glazing agent (hydroxypropyl methyl cellulose)], pyrroloquinoline quinone disodium salt, anti-caking agents (magnesium salts of fatty acids), D-pantothenate calcium (pantothenic acid), D-alpha-tocopheryl acid succinate (natural vitamin E), riboflavin (vitamin B2).
Warnings
Once opened, store in a cool (under 25ºC), dry and dark place. Do not exceed the stated recommended daily dose. Keep out of reach of the smallest children. Nutritional supplements should not be used to replace a balanced diet. This food supplement should only be consumed by adults, excluding pregnant and lactating women. It is necessary to maintain a varied and balanced diet and a healthy lifestyle.
PQQ (Pyrroloquinoline Quinone) 20mg from EssentialSeries is a dietary supplement in vegetable capsules developed from Pyrroloquinoline Quinone Disodium Salt, of high purity and derived from a natural source biosynthesized through a fermentation process. HSN's formula also contains B vitamins and Vitamin E, a powerful antioxidant.
Pyrroloquinoline Quinone is a relatively recent compound that has sparked great interest among top European experts in human nutrition quality and safety. This expert panel has established essential quality factors for PQQ to be suitable for use as a dietary supplement, and at HSN we developed our product considering all these criteria, to offer you as always: premium quality at a fair price.
HSN's PQQ comes from a bacterial fermentation process, but unlike other raw materials from such processes, our PQQ contains no genetically modified organisms: It is 100% GMO-Free.
Pyrroloquinoline Quinone (PQQ, for short) is a molecule with a quinone structure first identified as a enzyme cofactor in bacteria. This is a classic process of locating other vitamin-like compounds we already know, such as para-aminobenzoic acid (PABA).
PQQ in bacteria acts like a vitamin would in humans. In fact, when the compound was further studied, it was established as a 'new vitamin' in human nutrition, with the publication by Kasahara et al. (2003) in the prestigious scientific journal Nature. However, this claim was later rejected due to inconsistencies in the foundations, and it was limited to being called a 'vitamin-like' compound like PABA, Coenzyme Q10, or Choline.
PQQ in the human body is an enzyme cofactor with binding sites on a subtype of proteins called quinoproteins.
Although natural synthesis of Pyrroloquinoline Quinone and its use as a dietary supplement is relatively recent, its natural intake is traditional since it is intrinsically found in commonly consumed foods; PQQ can be found in soy and fermented soy products like Natto or Tofu; in spinach, mustard, tea, and even in human milk during lactation.
PQQ is a compound naturally present in our diet, and due to its valuable antioxidant power, it has been developed as a dietary supplement for consumption.
Natural PQQ present in foods exists in free form (as PQQ) or conjugated, and part of it is present in degraded form, as IPQ and other derivatives. All naturally occurring PQQ in foods is safe.
However, when it comes to developing dietary supplements, specific quality values must be guaranteed, which come from an appropriate biosynthesis process. The European Food Safety Authority has helped producers define how PQQ should be properly developed, and at HSN we have followed all established criteria.
So make sure the PQQ supplement you use meets these requirements to effectively and safely enjoy one of the most renowned antioxidants in human nutrition. Watch out! Because many companies don’t.
HSN’s PQQ has been developed following the criteria set out in the Scientific Opinion of the EFSA Panel on Dietetic Products, Nutrition and Allergies.
Our Pyrroloquinoline Quinone is not synthetic like most options on the American market that don’t meet these requirements; our PQQ is biosynthesized through a bacterial fermentation process.
By culturing the bacterium Hyphomicrobium denitrificans CK-275, a classic microorganism recognized as safe for human nutrition, naturally produced Pyrroloquinoline Quinone is obtained.
This process is carried out in a laboratory that maintains Good Manufacturing Practices (GMP) and Hazard Analysis and Critical Control Points (HACCP), using a non-genetically modified bacterial strain. The medium where PQQ is generated is centrifuged and purified through processes that are gentle on the compound, ensuring a final purity result >99.0%.
The compound’s purity can be checked by the natural color PQQ should have, which is a reddish tone, like the powder inside our vegetable capsules.
PQQ can be developed in different ways, and one of the most classic you’ll find in dietary supplements is synthetic Pyrroloquinoline.
HSN’s Pyrroloquinoline Quinone has been developed naturally, using the bacterial strain Hyphomicrobium denitrificans CK-275, through fermentation processes without using animal-derived compounds, making it a raw material fully suitable for vegan diets.
Also, the bacterial strain source has been carefully cultivated without the presence of Genetically Modified Organisms. The recognized organization 'GMO Project' classifies bacteria intended for food product development as elements in the 'High risk of containing Genetically Modified Organisms' category.
Well, our PQQ, as well as all elements used in its production process, are completely free of Genetically Modified Organisms.
Enjoy pure, naturally biosynthesized PQQ with HSN’s dietary supplement.
Pyrroloquinoline Quinone base has an associated problem, which is high reactivity. Keep in mind that being such a powerful antioxidant, when exposed to any pro-oxidative event (and there are many types): light exposure, oxygen, and other factors; it donates electrons, oxidizing itself and 'degrades'.
When PQQ degrades or reacts with amino acids and nucleophiles and converts to IPQ, it loses at least part of its functional properties, since biologically PQQ as such is required to act as a catalytic cofactor of lactate and other dehydrogenases in the conversion of NADH to NAD+ in the body, which has important physiological relevance (Jonscher et al., 2021).
The disodium salt form of PQQ stabilizes the compound, maintaining good bioavailability like PQQ base, but significantly improving resistance to environmental conditions that oxidize PQQ’s native state. The PQQ disodium salt powder can be stored stably, maintaining its purity longer and under conditions that require less control compared to PQQ base, demonstrating the quality of stability the disodium salt provides.
Absorbance is a compound’s ability to absorb light at a specific wavelength, which is a classic test to define characteristics of many compounds. In PQQ, it is especially relevant to characterize the compound’s quality, safety, and effectiveness.
The European Expert Commission was interested in this finding, as stated in their scientific opinion:
'The ratio of absorbance at two specific wavelengths (A233/A259 and A322/A259) allows differentiation between oxidized and reduced forms of PQQ. Both values confirm the compound’s identity and purity.'
The absorbance values at the established wavelengths confirm that the PQQ used in our dietary supplement is in a reduced form, therefore not oxidized and with all its antioxidant power intact.
The reduced form of PQQ is equivalent to the Ubiquinol form of Coenzyme Q10, that is, the biologically active form of the compound the body would naturally use as an enzyme cofactor, so the fact that absorbance analyses confirm the compound’s reduction in HSN’s formula is key to backing its quality and effectiveness.
The composition of HSN’s PQQ formula has been completed with vitamins that support its overall function, including:
Present in stable forms with high bioavailability for the body.
Adding vitamins contributes to the formula’s overall antioxidant properties, since thanks to vitamin E and riboflavin, it helps protect cells from oxidative damage.
Pantothenic acid also has a key function highly sought with this product’s use: it contributes to normal energy metabolism and normal intellectual performance.
A complete formula on all levels to enjoy the full benefits of the nutrients used.
The amounts of PQQ traditionally found in foods are quite low, with fermented soy derivatives standing out as the main dietary source of PQQ, yet their content is barely 60 ng/g.
HSN’s dietary supplement has been developed according to the recommended dose established in relevant scientific studies conducted in humans, such as:
Our R&D team uses the best and most recent scientific evidence on effectiveness and safety not only to select raw materials but also to establish the most suitable dose for developing dietary supplements.
PQQ is a dietary supplement established as safe in combination with other supplements, and no negative interactions are known with any compounds present in common dietary supplements, so you can easily add it.
Some of the most classic combinations with PQQ are:
Don’t miss the entire antioxidants catalog from HSN!
Scientific bibliography on PQQ
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Score of 4.7 / 5.00 of 47 real reviews
Pedro |
PQQ
Excellent product, for very diverse functions of the body. Antioxidant and sirtuin formation assistant. Rejuvenating. I will continue to take it. Best regards.
Pqq |
Energy input, more willingness
I can say that I have tried almost everything that comes on the market, out of curiosity rather than necessity and I can say that I have noticed a greater willingness to move during the day, as well as at the time of physical activity, I notice a higher level of energy and that extrapolates to better workouts, less fatigue in general. Good effect!
C-p. |
Very interesting
A type of supplementation that over time seems to show general improvements in our body and at a very good price.
Ángel |
PQQ
Supplement in the optimal amount, with antioxidant and preventive properties at the cardiovascular level and the need to increase energy. Better to combine with coenzymeQ10, for the benefits at the heart and energy level, as it also increases the absorption of the latter, along with pepper.
Alex |
Good product
In principle there are no noticeable effects at the external level, I understand that it is a product that works at the cellular level, and the changes are progressive at the internal level, then obviously over time there will be changes at the external level. When taking other supplements I could not evaluate with accuracy. But it feels good and is an excellent antioxidant.
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