•  100mg of Coenzyme Q10 in oxidised form (Ubiquinone) per vegetable capsule.
•  With BioPerine^® black pepper extract - Enhanced bioavailability.
•  Produced in vegetable capsules without gelatine - Suitable for vegan diets.
•  Supplemented formula with Vitamin B2 and Selenium for additional benefits.

Coenzyme Q10 100mg + BioPerine® - Get to Know It

Coenzyme Q10 100mg + BioPerine^® from EssentialSeries is a supplement in vegetable capsules, made from coenzyme Q10 in ubiquinone form, black pepper extract standardised to 98.5% piperine (BioPerine^®), vitamin B2 and L-selenomethionine.

Coenzyme Q10, also known as ubiquinone, is a molecule found in nearly all human cells. It is concentrated in tissues with high energy requirements, such as the heart, kidneys, liver, and muscles. Although the body naturally produces it, its production declines with age (Barcelos & Haas, 2019).

Coenzyme Q10 is a common dietary supplement for many, especially for those who do not consume large amounts of red meat or organ meats.

Discover HSN’s Classic CoQ10 Formula

What is CoQ10?

Coenzyme Q10, or CoQ10, is a fat-soluble substance naturally distributed throughout the body. Its chemical structure resembles that of vitamins, and its widespread distribution in tissues also gives it the name ubiquinone (from the Latin 'ubique,' meaning 'everywhere,' and the suffix '-quinone,' referencing its quinone-like chemical structure). The term “ubiquinone” is due to its pervasive presence in the body.

Over time, the body’s natural production of CoQ10 tends to decrease. Research has shown that its presence varies at different stages of ageing. While it is not classified as a vitamin since the body continues to produce it, it is recognised for its “semi-essentiality”. Factors like age, oxidative stress, and certain health conditions can impact its levels, making CoQ10 supplementation beneficial.

Standard Dose: 100mg

The 100mg dose of ubiquinone in supplements is considered standard due to studies showing that this quantity provides an optimal balance of efficacy and convenience.

This dose is sufficient to significantly raise CoQ10 levels in the body, particularly in individuals with low levels due to age or specific health conditions, without the risk of adverse effects. 100mg has become an ideal reference point for many users.

Ubiquinone Form

Coenzyme Q10, or ubiquinone, is a molecule found in cells, particularly concentrated in mitochondria, and plays a crucial role in energy production. This molecule exists in two interconvertible forms: ubiquinone (oxidised form) and ubiquinol (reduced form). Both forms participate in biological processes, though their chemical structure differentiates them.

Ubiquinone is the oxidised form of coenzyme Q10. Its structure enables it to accept electrons from other molecules during cellular processes, facilitating its conversion to the reduced form, ubiquinol. Ubiquinone is more stable in its oxidised form and is often found in the body in this stage of the conversion process. The transition between ubiquinone and ubiquinol is reversible and occurs constantly within the body, depending on energy needs and the cellular environment.

Formula with Vitamin B2 and Selenium - Why?

The inclusion of riboflavin and selenomethionine in the Coenzyme Q10 100mg + Bioperine^® product is due to the synergistic properties of these micronutrients with coenzyme Q10. Riboflavin, or vitamin B2, contributes to normal energy metabolism and helps reduce tiredness and fatigue. Meanwhile, selenomethionine, a source of selenium, supports normal spermatogenesis and the protection of cells from oxidative damage. These micronutrients work together with coenzyme Q10 for optimal support.

With BioPerine® - Maximum Bioavailability

Piperine, an alkaloid in black pepper, enhances Coenzyme Q10’s bioavailability by inhibiting the enzymes responsible for its metabolism and facilitating the absorption of fat-soluble nutrients, allowing a higher amount of Coenzyme Q10 to be absorbed. According to a study by Badmaev et al. (2000), combining piperine with Coenzyme Q10 significantly increased its absorption in humans compared to using it without piperine.

For the piperine source, we have chosen a classic from our catalogue: BioPerine^®.

How to Choose Coenzyme Q10? Dosage and Form

Ubiquinone is the standard form of Coenzyme Q10, but if you’re seeking something superior, you can opt for Ubiquinol, also available in our catalogue, featuring the world’s best raw material: Kaneka Ubiquinol™. It is essential to remember that ubiquinol requires more careful storage once opened at home. While it should be stored like ubiquinone, any storage issues (leaving the container open, exposure to sunlight, or high humidity) may lead to significant degradation.

You can purchase: Ubiquinol (Kaneka Ubiquinol™) 100mg at HSN.

If you prefer the traditional ubiquinone form, you can choose from:

•  100mg (this product): A standard dose, ideal for supplementing the diet with coenzyme Q10, including for older adults.
•  200mg: The higher concentration version is the best choice for those needing an extra CoQ10 boost, either due to significantly reduced synthesis (such as with monacolin use) or those following vegan diets with negligible Coenzyme Q10 intake. Find 200mg Coenzyme Q10 here.

Other Antioxidants - Discover New Options

You can complement Coenzyme Q10 intake with other compounds, including:

•  Vitamin E.
•  NADH.
•  PQQ.

More Products with the Same Purpose

If you’re looking for other products in the 'heart-circulation' category, you might consider:

•  OPC Complex.
•  Nattokinase.
•  Pycnogenol®.

Interesting Bibliography

•  Badmaev, V., Majeed, M., & Prakash, L. (2000). Piperine derived from black pepper increases the plasma levels of coenzyme Q10 following oral supplementation. The Journal of Nutritional Biochemistry, 11(2), 109–113.
•  Drug and Therapeutics Bulletin. (2015). Coenzyme Q10 and statin-related myopathy. BMJ: British Medical Journal, 53(5), 54–56.
•  Qu, H., Guo, M., Chai, H., Wang, W. T., Ga, Z. Y., & Shi, D. Z. (2018). Effects of coenzyme Q10 on statin-induced myopathy: An updated meta-analysis of randomized controlled trials. Journal of the American Heart Association, 7(19), e009835.
•  Barcelos, I. P., & Haas, R. H. (2019). CoQ10 and Aging. Biology, 8(2), 28.
•  Bhagavan, H. N., & Chopra, R. K. (2006). Coenzyme Q10: absorption, tissue uptake, metabolism and pharmacokinetics. Free Radical Research, 40(5), 445–453.
•  Sarmiento, A., Diaz-Castro, J., Pulido-Moran, M., Kajarabille, N., Guisado, R., & J. Ochoa, J. (2016). Coenzyme Q10 Supplementation and Exercise in Healthy Humans: A Systematic Review. Current Drug Metabolism, 17(4), 345–358.
•  Tabrizi, R., Akbari, M., Sharifi, N., Lankarani, K. B., Moosazadeh, M., Kolahdooz, F., … Asemi, Z. (2018). The Effects of Coenzyme Q10 Supplementation on Blood Pressures Among Patients with Metabolic Diseases: A Systematic Review and Meta-analysis of Randomized Controlled Trials. High Blood Pressure and Cardiovascular Prevention, 25(1), 41–50.
•  Zeng, Z. Y., Li, Y. P., Lu, S. Y., Huang, W. S., & Di, W. (2019). Efficacy of CoQ10 as supplementation for migraine: A meta-analysis. Acta Neurologica Scandinavica, 139(3), 284–293.