- High-quality phenylcapsaicin with aXivite®: formula with 10% pure phenylcapsaicin, microencapsulated to enhance absorption and tolerance.
- Vegetable capsule format: free from unnecessary additives, easy to take and suitable for vegans.
- Optimal and convenient dosage: each capsule contains 125mg of microencapsulated phenylcapsaicin. We recommend taking 2 capsules per day for a total intake of 250mg (2.5mg of pure phenylcapsaicin).
- Unbeatable format and price: you won’t find an aXivite® like this anywhere else—no one offers a larger quantity at a better price than we do.
- Innovative potential for athletes and fitness enthusiasts: phenylcapsaicin is a capsaicin-derived compound with advanced properties, considered a cutting-edge innovation.
- Compatible with other products: it is ideal for combining with pre-workout formulas and thermogenics to support their action.
- Next-generation product: aXivite® is one of the most innovative forms of capsaicin, used internationally by high-level athletes.
Phenylcapsaicin – Innovation and power in every capsule
Microencapsulated Phenylcapsaicin 125mg (aXivite®) by EssentialSeries is a food supplement in vegetable capsules made from microencapsulated phenylcapsaicin, featuring the aXivite® patent.
aXivite® is an innovative compound: Phenylcapsaicin, an analogue of capsaicin. Phenylcapsaicin is a patented molecule in which a natural phenyl group is used to stabilise a capsaicin identical to the natural version. Linked by a triple bond, the result is a natural capsaicin analogue, highly pure, with significantly reduced pungency (aXichem, n.d.).
HSN’s microencapsulated phenylcapsaicin is one of the most technologically advanced products in the food supplement industry today.
Harness the power of capsaicin with better tolerance
aXivite®: Microencapsulation for maximum versatility
aXivite® is a patented product by aXichem, known for developing a capsaicin analogue that surpasses conventional capsaicin by being completely free from contaminants, with maximum purity.
Thanks to its unique microencapsulation system, pungency—the characteristic 'heat' of capsaicin—is controlled. Microencapsulated phenylcapsaicin has been developed to provide specific release, allowing for a more versatile use of capsaicin.

As part of its patent protection trials, aXivite® has demonstrated very high bioavailability, producing a superior response compared to natural capsaicin, as measured by its blood concentration after ingestion at the same dose. Phenylcapsaicin has positioned itself as a more efficient alternative in terms of quantity-effect than natural capsaicin.
aXivite® is one of the biggest innovations in the industry, and HSN brings it to you with the highest manufacturing standards, in optimal doses, a practical format, and at a fair price. Compare and choose wisely!
10% pure phenylcapsaicin – what does this mean?
Microencapsulated aXivite® phenylcapsaicin contains 10% pure phenylcapsaicin.
When we talk about 10% pure phenylcapsaicin, we refer to the concentration of the active ingredient within the patented aXivite® formula. In the nutritional table, this percentage means that the recommended daily dose of 2 capsules provides 250mg of microencapsulated phenylcapsaicin, of which 2.5mg is pure phenylcapsaicin, the active bioactive compound.
Each capsule contains 125mg of aXivite®, meaning that one vegetable capsule provides 1.25mg of pure phenylcapsaicin, optimised for absorption thanks to the microencapsulation system that makes up the rest of the product content. This innovative technology allows phenylcapsaicin to be released more efficiently in the body, avoiding the irritating effects associated with other forms of capsaicin, without compromising quality.
This advanced format allows you to harness the nutritional benefits of capsaicin with higher bioavailability in a more practical way, making it an ideal option for athletes and individuals looking to use capsaicin without digestive discomfort.
In vegetable capsules: Vegan-friendly and free from unnecessary additives
We have developed our microencapsulated phenylcapsaicin in a vegetable capsule format, making it 100% suitable for vegans and compatible with all types of diets. Unlike other products that may contain animal-derived gelatines, we have chosen to use hydroxypropyl methylcellulose, a plant-based polymer.
Thanks to our controlled manufacturing in clean rooms, we guarantee the complete absence of cross-contamination with allergens of any kind, as well as a simple formulation without unnecessary additives for microencapsulation or encapsulation, free from aesthetic ingredients.
Key properties of phenylcapsaicin
Phenylcapsaicin is an innovative capsaicin derivative designed to offer an optimised experience compared to traditional dietary supplementation with capsaicin. Thanks to its improved molecular structure and its microencapsulation with the aXivite® patent, its stability and bioavailability are superior, allowing for optimal release.
This has made phenylcapsaicin a highly popular choice among athletes of all levels who seek the effects of capsaicin supplementation.
However, unlike conventional capsaicin, phenylcapsaicin has been developed to provide a more tolerable profile, making it a more appealing option for many users.
What makes phenylcapsaicin different from other forms of capsaicin?
At a molecular level, phenylcapsaicin differs from conventional capsaicin due to the addition of a phenyl group in its chemical structure. This modification alters its properties, resulting in greater stability and more efficient absorption. By modifying the original structure of capsaicin, phenylcapsaicin retains its functionality while reducing some of the characteristic effects of the base molecule, such as its high pungency. Thanks to this innovation, phenylcapsaicin has positioned itself as a compound with an optimised profile for use as a dietary supplement for athletes.
From a practical perspective, phenylcapsaicin offers significant advantages compared to other forms of capsaicin. Its higher bioavailability allows for more efficient absorption, optimising its effects with smaller doses. Additionally, the microencapsulation technology in aXivite® enhances its stability and tolerance, reducing the burning sensation typically associated with conventional capsaicin.
However, if you have a high tolerance for spicy foods and are familiar with traditional capsaicin, you can use it through the product:
The science behind phenylcapsaicin: studies and research
Phenylcapsaicin has attracted increasing interest in the scientific community, leading to the publication of various trials and reviews in the fields of sports supplementation and wellness. Due to its modified chemical structure and innovative microencapsulation technology, this compound has been the subject of studies analysing its bioavailability, stability, and tolerance compared to other forms of capsaicin.
Recent research has explored its potential in different applications, helping to build a body of evidence supporting its use in advanced formulations, not only as part of formulas but also as a standalone ingredient in dietary supplements like the product you are viewing.
What to combine phenylcapsaicin with?
Phenylcapsaicin can be combined with different ingredients depending on your goals. It is important to understand that there are no dietary supplements incompatible with this compound, meaning you can pair it with any product.
In the sports field, athletes commonly use it alongside:
To create pre-workout stacks designed for use before exercise sessions. These combinations allow for highly customised homemade stacks tailored to each athlete’s needs.
It can also be supplemented with products such as black pepper extract, which, thanks to its piperine content, enhances the absorption of phenylcapsaicin.
Additionally, it can be combined with electrolytes and BCAAs if the athlete is engaged in endurance sports.
References
- Jiménez-Martínez, P., Sánchez-Valdepeñas, J., Cornejo-Daza, P. J., Cano-Castillo, C., Asín-Izquierdo, I., Alix-Fages, C., … Colado, J. C. (2023). <a title='Effects of different phenylcapsaicin doses on neuromuscular activity and mechanical performance in trained male subjects: a randomized, triple-blinded, crossover, placebo-controlled trial' href='https://doi.org/10.3389/fphys.