NADH: cellular energy in its reduced form

NADH 50mg from EssentialSeries is a food supplement based on NADH and vitamins.

NADH, known as reduced nicotinamide adenine dinucleotide, is a coenzyme naturally present in the body. Its reduced form is the one involved in various processes in the body. Due to its structure, it’s a compound especially sensitive to light, heat, and acidic environments, which makes proper protection during digestion absolutely essential. That’s why our supplement is formulated with a special vegetable capsule that delays the release of its content until it reaches the intestinal environment.

An advanced way to complement your diet with NADH under optimized stability conditions.

Beta-NADH disodium salt: the most stable and studied form

The raw material we use is beta-NADH disodium salt, a stabilized form of the compound reducing its vulnerability to oxidation. This version is the most used in scientific studies, as it ensures higher quality.

At HSN we’re committed to quality, which is why we bring you an optimal raw material backed by scientific literature.

50mg per capsule: real concentration in every dose

Most NADH products you’ll find on the market provide very low amounts of the compound, usually between 2.5 mg and 10 mg per unit. At HSN we’ve formulated a capsule with 50 mg of NADH per dose, which means a significantly higher concentration than average.

Delayed release: maximum protection and optimal absorption

NADH is an extremely sensitive compound to factors like gastric acidity, light, and temperature. This poses a challenge for its formulation, since it can easily degrade before absorption if not properly protected.

A sensitive compound that needs care

Because of its reduced nature, NADH is unstable in the presence of acids and susceptible to oxidation. The delayed-release capsule acts as a barrier against the gastric environment, preserving the compound’s integrity during digestive transit.

This special coating prevents NADH from coming into contact with the stomach’s acidic content, where it would degrade quickly, and allows the compound to reach the small intestine in better condition.

Intestinal release to preserve its action

Thanks to this formulation, NADH is released in a part of the digestive tract where conditions are more favorable for its stability. Using delayed-release capsules helps optimize the ingredient’s effectiveness.

With antioxidant vitamins C and E

We’ve added vitamin C and vitamin E to our formula, two essential micronutrients with antioxidant properties that complement NADH’s action profile and provide extra benefits.

Meanwhile, vitamin E contributes to protecting cells from oxidative damage. Also, we use a natural form of vitamin E (D-alpha-tocopheryl succinate acid) for its quality and stability.

Ideal for athletes, older adults, and high-demand periods

We’ve formulated NADH 50mg thinking of people who want to include this ingredient in their daily routine with a practical, high-quality, and highly concentrated format.

It’s especially suitable for those going through periods of high physical or mental demand, whether due to intense training or situations that require an extra boost in nutrition care. It’s also widely used by older adults.

What supplements does it combine best with?

Some of the most common combinations are:

•  Ultra B-Complex: A complete B vitamin boost to support daily intake of key micronutrients.
•  Coenzyme Q10: A classic supplement that shares similar properties with NADH.
•  Stress Care: A unique HSN formula aimed at helping manage stress.
•  Magnesium bisglycinate: An essential mineral in one of the best forms available thanks to its good bioavailability.

Bibliographic references

•  Alegre, J., Rosés, J. M., Javierre, C., Ruiz-Baqués, A., Segundo, M. J., & Fernández De Sevilla, T. (2010). Nicotinamide adenine dinucleotide (NADH) in patients with chronic fatigue syndrome. Revista Clinica Espanola, 210(6), 284–288.
•  Gindri, I. de M., Ferrari, G., Pinto, L. P. S., Bicca, J., dos Santos, I. K., Dallacosta, D., & de Mello Roesler, C. R. (2024). Evaluation of safety and effectiveness of NAD in different clinical conditions: a systematic review. American Journal of Physiology - Endocrinology and Metabolism, 326(4), E417–E427.
•  Schiuma, G., Lara, D., Clement, J., Narducci, M., & Rizzo, R. (2024). Nicotinamide Adenine Dinucleotide: The Redox Sensor in Aging-Related Disorders. Antioxidants and Redox Signaling.
•  She, J., Sheng, R., & Qin, Z. H. (2021). Pharmacology and Potential Implications of Nicotinamide Adenine Dinucleotide Precursors. Aging and Disease, 12(8), 1879–1897.
•  White, A. T., & Schenk, S. (2012). NAD +/NADH and skeletal muscle mitochondrial adaptations to exercise. American Journal of Physiology - Endocrinology and Metabolism, 303(3), E308-21.