- Natural spermidine from wheat germ. Standardised vegetable source.
- Extract 50 times more concentrated. 1% spermidine guaranteed.
- 2.5mg of pure Spermidine net content per vegetable capsule.
- With Zinc and Vitamin B1 to complement the action of the compound.
- In vegetable capsules made from cellulose derivatives. 100% Vegan.
- No cosmetic additives. Only the necessary ingredients to make the capsules.
- High concentration per capsule. 2.5mg of Spermidine in line with scientific research.1
- With all HSN manufacturing quality guarantees. GMO-Free Guaranteed!
Spermidine. We'll tell you all about it!
Spermidine 2.5mg by EssentialSeries is a food supplement in vegetable capsules based on natural wheat germ extract with a guaranteed content of Spermidine, zinc citrate, and thiamine HCl.
Spermidine is a compound that, despite all its research and the recommendations of experts in the field over decades in Asia, is not very well known. It is a polyamine that is associated with multiple molecular actions in the body and whose concentration decreases with age.
Spermidine 2.5mg is a product with natural spermidine and without synthetic compounds like other brands on the market.
Quality + Safety. It has it all
At HSN we take the quality of the food supplements we provide you with very seriously, how do we ensure this?
Natural spermidine from wheat germ. Say goodbye to synthetic compounds
Spermidine is an amine that is present in very few natural foods, and in those where it is present, its concentration is extremely low.
This is why to develop a food supplement based on natural spermidine, you need a development team that has in-depth knowledge of the processing and development of the right raw materials to deliver what HSN's product offers you:
High concentration + natural source + assured content.
The spermidine in our product, unlike most other options on the market, is natural, coming from 50 times more concentrated extract of wheat germ grown under controlled conditions, without Genetically Modified Organisms during cultivation, to ensure the highest possible spermidine content in its germ.
A guaranteed 1%, although it may not seem like much, provides 2.5mg of natural spermidine per capsule.
2.5mg of spermidine per capsule. Why this dose?
Most scientific studies carried out on the use of spermidine have established minimum quantities of around 1mg of spermidine:
- Schwarz, C., et al. (2022). Effects of Spermidine Supplementation on Cognition and Biomarkers in Older Adults With Subjective Cognitive Decline: A Randomized Clinical Trial. JAMA network open, 5(5), e2213875.
- Wirth, M., Benson, G., Schwarz, C., Köbe, T., Grittner, U., Schmitz, D., Sigrist, S. J., Bohlken, J., Stekovic, S., Madeo, F., & Flöel, A. (2018). The effect of spermidine on memory performance in older adults at risk for dementia: A randomized controlled trial. Cortex; a journal devoted to the study of the nervous system and behavior, 109, 181–188.
Safety is established up to much higher doses, but effectiveness starts from at least a milligram.
In fact, general recommendations are based on the use of around 2.5mg per day, the dose at which we have developed our product, according to the most current and significant scientific evidence in humans.
Most spermidine products on the market provide low concentrations, typically between 0.4 and 1mg, as their product does not have the quality of HSN's supplement:
- If they are natural: they use worse extracts, sometimes with unsecured standardisations, which, in addition to being ineffective, can be dangerous.
- If they are synthetic: manufacturing is sometimes extremely expensive, making the price of as little as 1 mg prohibitive for users.
At HSN we do the best:
We bring you a wheat extract with natural spermidine, guaranteed high content, with guaranteed concentration, and at an unbeatable price.
Stick with HSN!!
In easy-to-swallow vegetable capsules. No gelatine! The real revolution in products suitable for vegan diets.
The capsules in which most food supplements on the market are presented are made from gelatine.
This is not a bad thing in itself, but it does make the product unsuitable for consumption by vegetarians and vegans, but.... At HSN we think it's a shame, don't you?
Why should a product containing compounds suitable for vegan diets cease to be vegan just because it uses a gelatine-based coating compound?
We have options that are equally valid and suitable for vegans!
At HSN we use HPMC, a vegetable cellulose derivative that is an excellent choice for coating powders, in capsules, with maximum strength, making them suitable for vegan diets.
GMO-Free. Free from Genetically Modified Organisms, guaranteed
Did you know that wheat germ with a high spermidine content belongs to the high-risk category group of Genetically Modified Organisms?
At HSN we use only the best raw materials, carefully selected to develop the best food supplements on the market.
Enjoy a highly concentrated extract of a premium wheat germ, standardised to 1% spermidine.
Spermidine 2.5mg is a product by HSN with proven properties
Spermidine is a well-studied compound with many scientific studies in the field of food supplements for people, especially the elderly.
In addition, the formula has been supplemented with 2 key nutrients to support the action of spermidine:
- Zinc: Zinc contributes to normal DNA synthesis.
- Vitamin B1: Thiamine contributes to normal energy metabolism.
Both nutrients are selected from high nutritional quality sources, because as with wheat extract, at HSN we only use the best forms of nutrients for the highest nutritional quality.
Combine it with other highly recommended products together!
Spermidine goes very well with certain food supplements, of which there are 3 that are perfect for use in combination with natural spermidine. These are:
Bibliographical References
- Ni, Y. Q., & Liu, Y. S. (2021). New Insights into the Roles and Mechanisms of Spermidine in Aging and Age-Related Diseases. Aging and Disease, 12(8), 1948–1963.
- Madeo, F., Bauer, M. A., Carmona-Gutierrez, D., & Kroemer, G. (2019). Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans? Autophagy, 15(1), 165–168.
- Filfan, M., Olaru, A., Udristoiu, I., Margaritescu, C., Petcu, E., Hermann, D. M., & Popa-Wagner, A. (2020). Long-term treatment with spermidine increases health span of middle-aged Sprague-Dawley male rats. GeroScience, 42(3), 937–949.
- Madeo, F., Eisenberg, T., Pietrocola, F., & Kroemer, G. (2018). Spermidine in health and disease. Science, 359(6374).
- Madeo, F., Hofer, S. J., Pendl, T., Bauer, M. A., Eisenberg, T., Carmona-Gutierrez, D., & Kroemer, G. (2020). Nutritional Aspects of Spermidine. Annual Review of Nutrition, 40, 135–159.
- Madeo, F., Carmona-Gutierrez, D., Kepp, O., & Kroemer, G. (2018). Spermidine delays aging in humans. Aging, 10(8), 2209–2211.
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