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SAFFRON EXTRACT affron® (3:1)

Essential Series

Saffron extract (affron®). 3 times more concentrated. 3.5% Lepticrosalides®. Saffron stigma extract. Origin: 100% Spain. AFF® ON Cool-Tech cold extraction system. With vitamin B12. Suitable for vegan diets.

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Remarkable aspects:

Gluten Free

Gluten Free

Nut Free

Nut Free

Soy Free

Soy Free

Lactose Free

Lactose Free

Suitable for Vegetarians

Suitable for Vegetarians

Fish Free

Fish Free

Suitable for Vegans

Suitable for Vegans

Dairy Free

Dairy Free

Without GMOs

Without GMOs

Egg Free

Egg Free

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Product information

  • Saffron Extract.
  • affron® raw material.
  • 3:1 extraction ratio.
  • 3.5% Lepticrosalides®.
  • With vitamin B12.
  • Vegan-friendly.

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Full description
Table of contents
    • Saffron Extract.
    • affron® raw material.
    • 3:1 extraction ratio.
    • 3.5% Lepticrosalides®.
    • With vitamin B12.
    • Vegan-friendly.

    What is affron® Saffron Extract (3:1)?

    affron® Saffron Extract (3:1) by EssentialSeries is a dietary supplement based on saffron stigma extract and vitamin B12.

    affron® is a premium saffron extract standardised to 3.5% of Lepticrosalides®, by HPLC (Pharmactive Biotech Products, s.f.).

    This product is suitable for vegan diets.

    Properties of saffron

    • Saffron contributes to emotional balance.
    • Saffron helps support relaxation.
    • Saffron helps maintain a positive mood.
    • Saffron stimulates libido.
    • Saffron helps maintain comfort before and during the menstrual cycle.

    Vitamin B12

    • Vitamin B12 contributes to normal energy metabolism.
    • Vitamin B12 contributes to normal nervous system function.
    • Vitamin B12 contributes to normal psychological function.
    • Vitamin B12 helps to reduce tiredness and fatigue.

    Why buy Saffron Extract from HSN?

    Authentic affron®

    Our saffron extract is manufactured with the exclusive affron® raw material, from Pharmactive Biotech Products S.L.U., a raw material recognised the world over for the great application it's demonstrated in scientific studies since the beginning of its development.

    We don't use any saffron raw materials other than the affron®. All of the product's saffron extract content is standardised in the proprietary mixture of crocins and safranal from the manufacturer Pharmactive: Lepticrosalides®.

    affron is made from 100% Spanish saffron (Crocus sativus L.), with certified national DNA. And it's classified with the international patent WO2017182688A1.

    Lepticrosalides®

    Pharmactive has had a large volume of scientific studies carried out using its trademarked affron® product.

    For the development of this raw material, the company that owns the label has developed a proprietary blend of two of the most recognised compound families of the saffron stigma: crocin and safranal, determined by HPLC-DAD. It's known as Lepticrosalides®.

    The affron® blend, developed under the intellectual property standards of the owner, has been used in 8 clinical studies with more than 400 subjects.

    1. Lopresti, A. L., & Drummond, P. D. (2017). Efficacy of curcumin, and a saffron/curcumin combination for the treatment of major depression: A randomised, double-blind, placebo-controlled study. Journal of Affective Disorders, 207, 188–196.
    2. Kell, G., Rao, A., Beccaria, G., Clayton, P., Inarejos-García, A. M., & Prodanov, M. (2017). affron® a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomized, placebo-controlled clinical trial. Complementary Therapies in Medicine, 33, 58–64.
    3. Nishide, A., Fujita, T., Nagaregawa, Y., Shoyama, Y., Ohnuki, K., Shimizu, K., … Ohnuki, K. (2018). Sleep enhancement by saffron extract in randomized control trial. Japanese Pharmacology and Therapeutics, 46(8), 1407–1415.
    4. Lopresti, A. L., Smith, S. J., Hood, S. D., & Drummond, P. D. (2019). Efficacy of a standardised saffron extract (affron®) as an add-on to antidepressant medication for the treatment of persistent depressive symptoms in adults: A randomised, double-blind, placebo-controlled study. Journal of Psychopharmacology, 33(11), 1415–1427.
    5. Lopresti, A. L., Smith, S. J., Metse, A. P., & Drummond, P. D. (2020). Effects of saffron on sleep quality in healthy adults with self-reported poor sleep: A randomized, double-blind, placebo-controlled trial. Journal of Clinical Sleep Medicine, 16(6), 937–947.
    6. Lopresti, A. L., Drummond, P. D., Inarejos-García, A. M., & Prodanov, M. (2018). affron®, a standardised extract from saffron (Crocus sativus L.) for the treatment of youth anxiety and depressive symptoms: A randomised, double-blind, placebo-controlled study. Journal of Affective Disorders, 232, 349–357.
    7. Almodóvar, P., Briskey, D., Rao, A., Prodanov, M., & Inarejos-García, A. M. (2020). Bioaccessibility and Pharmacokinetics of a Commercial Saffron (Crocus sativus L.) Extract. Evidence-Based Complementary and Alternative Medicine, 2020, 1575730.
    8. Lopresti, A. L., & Smith, S. J. (2021). The Effects of a Saffron Extract (affron®) on Menopausal Symptoms in Women during Perimenopause: A Randomised, Double-Blind, Placebo-Controlled Study. Journal of Menopausal Medicine, 27(2), 66.

    Industry leading R&D

    affron® is a raw material that uses a proprietary extraction process: AFF® ON Cool-Tech.

    This process allows affron® to have a higher concentration of chemical constituents of the plant thanks to its low temperature extraction.

    This technique helps obtain a superior quality saffron with:

    • Less industrial processing,
    • Less energy expenditure,
    • And no chemical use.

    As the solvent used is natural, according to the information provided by the manufacturer Pharmactive Biotech Products, S.L.U.

    Award winning

    affron® has won a number of renowned awards in the food industry:

    • Nutraingedients USA Awards, 2020.
    • Best Practices Award 2020, from Frost & Sullivan.
    • Nie Awards Winner, 2020.

    Thanks to the innovation of this raw material.

    Guaranteed effective dose

    Scientific studies carried out with affron®, the saffron extract of Pharmactive Biotech Products, S.L.U., have set 28 mg / day as the established dose.

    Our saffron extract provides 30mg of pure affron® per capsule, thus ensuring a sufficient dose of the award-winning raw material according to manufacturer recommendations.

    Vegan-friendly

    Our saffron extract doesn't contain any allergens listed in EU regulation 1169/2011 and is 100% suitable for vegan diets.

    What can you combine this product with?

    You can use it with:

    The questions are asked by users and the answers are prepared by the HSN team for informational purposes. The information provided does not replace the advice or care of a healthcare professional. References to food supplements have not been evaluated by the EFSA (European Food Safety Authority) and are not intended to diagnose, treat, cure, or prevent any disease. HSN reserves the right to review or update the answers when necessary.

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    Questions from other clients (0)

    What our customers say about the product

    SAFFRON EXTRACT affron® (3:1)

    A satisfied customer says:

    Good antidepressant

    Jorge | 19/02/2023

    I didn't know that such a widely used condiment existed as a supplement to improve mood. It works quite well after the second week.

    Desconocía que un condimento tan usado existía como suplemento para mejorar el estado anímico. Funciona bastante bien a partir de las segunda semana.
    Has the review helped you?
    SAFFRON EXTRACT affron® (3:1)

    A critical customer says:

    It is not clear to me that it will have an effect

    Ana | 15/06/2023

    One pill at night, it stains the urine, but I was still sleeping badly until I took vitamin D3, they also say it works well with premenstrual syndrome and hormonal imbalance. In my case I have not seen these effects, which I have achieved with other supplements such as vitex or vitamin D3. I think I will be a while without taking it and I will see if I really need it or not.

    Una pastilla por la noche, tiñe la orina, pero dormir seguía durmiendo mal hasta que me tomé la vitamina D3, también dicen que va bien con el síndrome premenstrual y el desequilibrio hormonal. En mi caso no he visto estos efectos, que si he conseguido con otros complementos como el vitex o la vitamina D3. Creo que estaré un tiempo sin tomarlo y veré si realmente lo necesito o no.
    Has the review helped you?

    Score of 4.65 / 5.00 of 23 real reviews

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    The product reviews and opinions published reflect only the customers’ views and experiences. HSN does not verify or endorse such comments or claims, and is not responsible for the content provided in the reviews. Statements regarding food supplements have not been evaluated by the EFSA (European Food Safety Authority) and are not intended to diagnose, treat, cure, or prevent any disease or medical condition.

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    Irene |

    VERIFIED OPINION

    SAFFRON EXTRACT affron® (3:1)

    It works!

    I started taking it to regulate my mood during perimenopause and after several weeks I can say that it works!

    Empecé a tomarlo para regular mi estado de ánimo en perimenopausia y tras varias semanas ¡puedo decir que funciona!
    Has the review helped you?
    General satisfaction (5.0 / 5)
    Results (5.0 / 5)
    Value/Price (5.0 / 5)
    Packaging (5.0 / 5)

    Mauricio |

    VERIFIED OPINION

    SAFFRON EXTRACT affron® (3:1)

    Excellent

    Great product, arrived very quickly, excellent value for money and very well packaged, I recommend it!!!

    Ótimo produto, chegou muito rápido, excelente custo benefício e muito bem embalado, recomendo!!
    Has the review helped you?
    General satisfaction (5.0 / 5)
    Results (5.0 / 5)
    Value/Price (5.0 / 5)
    Packaging (5.0 / 5)

    Sully |

    VERIFIED OPINION

    SAFFRON EXTRACT affron® (3:1)

    Doubt

    It seems to me that it helps somewhat in terms of stress, but I think it would have to be combined with other supplements to be more effective.

    Me parece que algo ayuda en cuanto al stress creo que habría que combinarlo con otros suplementos para que sea más efectivo.
    Has the review helped you?
    General satisfaction (4.3 / 5)
    Packaging (5.0 / 5)
    Results (4.0 / 5)
    Value/Price (4.0 / 5)

    Oscar |

    VERIFIED OPINION

    SAFFRON EXTRACT affron® (3:1)

    Excellent

    Very good value for money product, it is of much better quality than other products of other brands.

    Buenisimo producto calidad precio, es de muchisima mas calidad que otro producto de otras marcas.
    Has the review helped you?
    General satisfaction (5.0 / 5)
    Results (5.0 / 5)
    Value/Price (5.0 / 5)
    Packaging (5.0 / 5)

    Salvador |

    VERIFIED OPINION

    SAFFRON EXTRACT affron® (3:1)

    Strong product

    The product is well suited for improving sleep, depressive moods and fertility in women in general.

    Das Produkt eignet sich gut für die Verbesserung des Schlafes, depressiver Verstimmungen und allgemein auch der Fertilität der Frau.
    Has the review helped you?
    General satisfaction (5.0 / 5)
    Results (5.0 / 5)
    Value/Price (5.0 / 5)
    Packaging (5.0 / 5)
    See all reviews

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