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SAFFRON EXTRACT affron® (3:1)

Essential Series

Saffron extract (affron®). 3 times more concentrated. 3.5% Lepticrosalides®. Saffron stigma extract. Origin: 100% Spain. AFF® ON Cool-Tech cold extraction system. With vitamin B12. Suitable for vegan diets.

(20 opinions)

Gluten Free

Gluten Free

Nut Free

Nut Free

Soy Free

Soy Free

Lactose Free

Lactose Free

Suitable for Vegetarians

Suitable for Vegetarians

Fish Free

Fish Free

Suitable for Vegans

Suitable for Vegans

Dairy Free

Dairy Free

Without GMOs

Without GMOs

Egg Free

Egg Free

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Product information

  • Saffron Extract.
  • affron® raw material.
  • 3:1 extraction ratio.
  • 3.5% Lepticrosalides®.
  • With vitamin B12.
  • Vegan-friendly.

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Full description
Table of contents
    • Saffron Extract.
    • affron® raw material.
    • 3:1 extraction ratio.
    • 3.5% Lepticrosalides®.
    • With vitamin B12.
    • Vegan-friendly.

     

    What is affron® Saffron Extract (3:1)?

    affron® Saffron Extract (3:1) by EssentialSeries is a dietary supplement based on saffron stigma extract and vitamin B12.

    affron® is a premium saffron extract standardised to 3.5% of Lepticrosalides®, by HPLC (Pharmactive Biotech Products, s.f.).

    This product is suitable for vegan diets.

    Properties of saffron

    • Saffron contributes to emotional balance.
    • Saffron helps support relaxation.
    • Saffron helps maintain a positive mood.
    • Saffron stimulates libido.
    • Saffron helps maintain comfort before and during the menstrual cycle.

    Vitamin B12

    • Vitamin B12 contributes to normal energy metabolism.
    • Vitamin B12 contributes to normal nervous system function.
    • Vitamin B12 contributes to normal psychological function.
    • Vitamin B12 helps to reduce tiredness and fatigue.

    Why buy Saffron Extract from HSN?

    Authentic affron®

    Our saffron extract is manufactured with the exclusive affron® raw material, from Pharmactive Biotech Products S.L.U., a raw material recognised the world over for the great application it's demonstrated in scientific studies since the beginning of its development.

    Logo affron

    We don't use any saffron raw materials other than the affron®. All of the product's saffron extract content is standardised in the proprietary mixture of crocins and safranal from the manufacturer Pharmactive: Lepticrosalides®.

    affron is made from 100% Spanish saffron (Crocus sativus L.), with certified national DNA. And it's classified with the international patent WO2017182688A1.

    Lepticrosalides®

    Pharmactive has had a large volume of scientific studies carried out using its trademarked affron® product.

    For the development of this raw material, the company that owns the label has developed a proprietary blend of two of the most recognised compound families of the saffron stigma: crocin and safranal, determined by HPLC-DAD. It's known as Lepticrosalides®.

    The affron® blend, developed under the intellectual property standards of the owner, has been used in 8 clinical studies with more than 400 subjects.

    1. Lopresti, A. L., & Drummond, P. D. (2017). Efficacy of curcumin, and a saffron/curcumin combination for the treatment of major depression: A randomised, double-blind, placebo-controlled study. Journal of Affective Disorders, 207, 188–196.
    2. Kell, G., Rao, A., Beccaria, G., Clayton, P., Inarejos-García, A. M., & Prodanov, M. (2017). affron® a novel saffron extract (Crocus sativus L.) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomized, placebo-controlled clinical trial. Complementary Therapies in Medicine, 33, 58–64.
    3. Nishide, A., Fujita, T., Nagaregawa, Y., Shoyama, Y., Ohnuki, K., Shimizu, K., … Ohnuki, K. (2018). Sleep enhancement by saffron extract in randomized control trial. Japanese Pharmacology and Therapeutics, 46(8), 1407–1415.
    4. Lopresti, A. L., Smith, S. J., Hood, S. D., & Drummond, P. D. (2019). Efficacy of a standardised saffron extract (affron®) as an add-on to antidepressant medication for the treatment of persistent depressive symptoms in adults: A randomised, double-blind, placebo-controlled study. Journal of Psychopharmacology, 33(11), 1415–1427.
    5. Lopresti, A. L., Smith, S. J., Metse, A. P., & Drummond, P. D. (2020). Effects of saffron on sleep quality in healthy adults with self-reported poor sleep: A randomized, double-blind, placebo-controlled trial. Journal of Clinical Sleep Medicine, 16(6), 937–947.
    6. Lopresti, A. L., Drummond, P. D., Inarejos-García, A. M., & Prodanov, M. (2018). affron®, a standardised extract from saffron (Crocus sativus L.) for the treatment of youth anxiety and depressive symptoms: A randomised, double-blind, placebo-controlled study. Journal of Affective Disorders, 232, 349–357.
    7. Almodóvar, P., Briskey, D., Rao, A., Prodanov, M., & Inarejos-García, A. M. (2020). Bioaccessibility and Pharmacokinetics of a Commercial Saffron (Crocus sativus L.) Extract. Evidence-Based Complementary and Alternative Medicine, 2020, 1575730.
    8. Lopresti, A. L., & Smith, S. J. (2021). The Effects of a Saffron Extract (affron®) on Menopausal Symptoms in Women during Perimenopause: A Randomised, Double-Blind, Placebo-Controlled Study. Journal of Menopausal Medicine, 27(2), 66.

    Industry leading R&D

    affron® is a raw material that uses a proprietary extraction process: AFF® ON Cool-Tech.

    This process allows affron® to have a higher concentration of chemical constituents of the plant thanks to its low temperature extraction.

    This technique helps obtain a superior quality saffron with:

    • Less industrial processing,
    • Less energy expenditure,
    • And no chemical use.

    As the solvent used is natural, according to the information provided by the manufacturer Pharmactive Biotech Products, S.L.U.

    Award winning

    affron® has won a number of renowned awards in the food industry:

    • Nutraingedients USA Awards, 2020.
    • Best Practices Award 2020, from Frost & Sullivan.
    • Nie Awards Winner, 2020.

    Thanks to the innovation of this raw material.

    Guaranteed effective dose

    Scientific studies carried out with affron®, the saffron extract of Pharmactive Biotech Products, S.L.U., have set 28 mg / day as the established dose.

    Our saffron extract provides 30mg of pure affron® per capsule, thus ensuring a sufficient dose of the award-winning raw material according to manufacturer recommendations.

    Vegan-friendly

    Our saffron extract doesn't contain any allergens listed in EU regulation 1169/2011 and is 100% suitable for vegan diets.

    What can you combine this product with?

    You can use it with:

    Questions from other clients (0)

    What our customers say about the product

    SAFFRON EXTRACT affron® (3:1)

    A satisfied customer says:

    Excellent

    Oscar | 26/06/2025

    Very good value for money product, it is of much better quality than other products of other brands.

    Buenisimo producto calidad precio, es de muchisima mas calidad que otro producto de otras marcas.
    Has the opinion helped you?
    SAFFRON EXTRACT affron® (3:1)

    A critical customer says:

    Quality

    Buen producto | 23/04/2023

    the capsules are very convenient because they are small in size. After using it for more than a month, I am slowly starting to see some effects. Clearly it is not immediate. You have to wait and little by little you start to feel more relaxed.

    las capsulas son muy cómodas porque son de tamaño pequeño. Después de utilizarlo más de un mes, poco a poco empiezo a ver algunos efectos. Claramente no se trata de algo inmediato. Tienes que esperar y poco a poco empiezas a sentirte más relajado.
    Has the opinion helped you?

    Score of 4.65 / 5.00 of 20 real reviews

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    Oscar |

    Excellent

    Very good value for money product, it is of much better quality than other products of other brands.

    Buenisimo producto calidad precio, es de muchisima mas calidad que otro producto de otras marcas.
    Has the opinion helped you?
    General satisfaction (5.0 / 5)
    Results (5.0 / 5)
    Value/Price (5.0 / 5)
    Packaging (5.0 / 5)

    Salvador |

    Strong product

    The product is well suited for improving sleep, depressive moods and fertility in women in general.

    Das Produkt eignet sich gut für die Verbesserung des Schlafes, Depressive Verstimmungen und allgemein auch der Fertilität der Frau.
    Has the opinion helped you?
    General satisfaction (5.0 / 5)
    Results (5.0 / 5)
    Value/Price (5.0 / 5)
    Packaging (5.0 / 5)

    Carmen |

    Cash

    It helps me to fall asleep and to control the nervous system, with only one pill it fulfills my sleep objective. Very good supplement, I will continue to use it.

    Me ayuda a conciliar el sueño y a controlar el sistema nervioso, con sólo una pastilla cumple sueño objetivo. Muy buen suplemento, seguiré utilizándolo.
    Has the opinion helped you?
    General satisfaction (5.0 / 5)
    Results (5.0 / 5)
    Value/Price (5.0 / 5)
    Packaging (5.0 / 5)

    BLP |

    Good product

    Small capsules, easy to swallow. It is a little early to assess the effectiveness but it looks good.

    Cápsulas pequeñas, fácil de tragar. Es un poco pronto para valorar la efectividad pero tiene buena pinta.
    Has the opinion helped you?
    General satisfaction (4.7 / 5)
    Value/Price (5.0 / 5)
    Packaging (5.0 / 5)
    Results (4.0 / 5)

    Maria |

    Great

    It is a great supplement to lift your mood, as it is a natural antidepressant. I don't take it every day, but only about 3 days a week to avoid tolerance, or more often if the situation requires it. I have depression but I can't take antidepressants because they produce side effects, and saffron is a salvation!

    Es un suplemento genial para levantar el estado de ánimo, ya que es un antidepresivo natural. No lo tomo todos los días, sino solo unos 3 dias a la semana para evitar tolerancia, o algo más seguido si la situación lo requiere. Tengo depresión pero no puedo tomar antidepresivos porque me producen efectos secundarios, y azafrán es una salvación!
    Has the opinion helped you?
    General satisfaction (5.0 / 5)
    Results (5.0 / 5)
    Value/Price (5.0 / 5)
    Packaging (5.0 / 5)
    See all reviews

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